The Tobacco Industry Profiting From Death - 1091 Words

The tobacco industry in America is one that every person is affected by. In the past year over 3,000 people died from second-hand smoke related deaths (Above the Influence.com). Even non-smokers are heavily affected by this moneymaking industry. The real question though, is how is a product that kills justified in the market? This product is not only addictive, but also highly threatening to the lives of its users. The majority of users do not realize it, but in reality they are paying for their own funeral. Tobacco and cigarette companies continue to feed lies to the public through their marketing strategies and product makeup. Hidden documents containing information on the toxicity and pharmacological properties of nicotine†¦show more content†¦The surgeon general warnings on a pack of cigarettes expose many of the astonishing effects of smoking. With the massive amount of knowledge and warnings publicized, why has a significant impact not been made on the lives of smoker s? In the past year over 440,000 people died from smoking cigarettes, in which the majority were people that began smoking before they were 18 years old (Above the Influence.com). The clear scientific fact that the tobacco industry targets adolescents is an epidemic that needs to be stopped. An experiment was taken with a base consisting of people under the age of 18 that had never smoked a cigarette. The study showed that after several years, the majority of the original people reported that they either had tried a cigarette, or would have if it was presented to them (Pierce). The experiment proved the targeting of adolescents by cigarette and tobacco companies. Living on a college campus of over 25,000 students, it is clear that the tobacco industry affects us all. Whether it is an addiction to cigarettes, the use of other tobacco products, or second hand smoke that we are forced to inhale, we are all influenced and subjected to the tobacco industry’s harms. We all see the cigarette butts covering campus, people walking to class with a cigarette in their hand, or even a hookah being smoked outside on the benches. It is evident that the tobacco industry has reached many when it comes to college campuses. It has become clear that theShow MoreRelated Tobacco Essay905 Words   |  4 PagesA PAPER REGARDING THE TOBACCO INDUSTRY (3 PAGES). The Killing Business? This paper is about the tobacco industry. Some would find that the label ‘killing business’ is very appropriate. Others would say that that name is misleading and inaccurate. Biased, I am not. So we will look at the issue in regards to the industry from both consumer and producer points of perspective with fairness and equality in reach. With an open mind now, let’s peer closer at the aftermath tobacco has left us standing inRead MoreShould Big Tobacco Be Sued for Health Care Bills? An Analysis998 Words   |  4 Pages Should big tobacco be sued for health bill? An analysis A recent ruling by the Supreme Court of Canada on the subject of smoking is the main topic of my articles. The landmark ruling made on September 30th gives the province of British Columbia ammunition against big tobacco companies. The decision allows British Columbia to sue tobacco companies for damages related to smoking-related health care costs dating back 50 years (Bell Globalmedia Inc [BGMI], 2005). Many expect theRead MoreArgumentative Essay About Marijuana1308 Words   |  6 Pagessimple. Weed indeed proves to be beneficial and should not be prohibited or illegal. Society shames Cannabis smokers because it is inhaled the same way as tobacco, and those that are against it have developed the notion that it is bad for people’s health. However, society fails to realize that Marijuanas effects are helpful and not any different from any other drug as it fights off illnesses, lacks addictive chemicals and qualities, can be used productively, and legalization makes it chall enging forRead MoreShould Marijuana Be Legalized?1121 Words   |  5 Pagesstarting to resurface. Keeping this drug illegal could cause more problems for Mississippi. Fully legalizing marijuana, while making it limited with restrictions could stimulate our economy. By abolishing the ban on marijuana use and treating it like tobacco and alcohol, the state would receive immediate and long-term benefits. Marijuana can be used as a medical plant to help people who are in need. Marijuana is a naturally found plant that is identified all around the world. This plant is perceivedRead MoreInjustice And Power Imbalances Between Africa And Europe1436 Words   |  6 Pagesinvestment for major European powerhouses such as the British Russian empires, the so-called â€Å"Scramble for Africa† was a major part of the late 1800’s. This was not without some degree of racism, as Europeans were quick to buy cheap, if not free, labor from the indigenous populations and use rivalries between groups to further divide and conquer the country. The balance of power between Africa and Europe continued to shift unfairly as colonization continued, and left lasting effects on both continents;Read MoreShould Marijuana Be Legal?1793 Words   |  8 PagesNearly 100 million people in the united states have used marijuana. This past year government surveys have found that over 14 million Americans smoke marijuana despite the strict laws due to it being a schedule 1 drug. Behind alcohol and tobacco, marijuana is the third most accepted recreational drug. The United States of America’s current marijuana policies do not reflect the reality that almost one third of the entire country’s population supports the legalization of marijuana. This vast majorityRead More Alcohol Consumption Essay2409 Words   |  10 Pageseach year roughly 13,400 people die and an additional 255,500 are injured in motor vehicle crashes involving an alcohol-impaired driver according to Burris et al., 2011. In 2006, these crashes accounted for almost a third of all U.S. traffic-related deaths (Burris et al., 2011). Alcohol is the most commonly abused substance in the United States according to Pandrea, Happel, Amedee, Bagby, Nelson, 2010, and studies show that reducing alcohol consumption can lead to public health improvements suchRead MoreEffective Understanding of Cultural Differences Will Be Key to Successful Business Operations in the 21st Century. Discuss This Statement Using Examples from Two Sectors.4254 Words   |  18 Pagescentury. Discuss this statement using examples from two sectors. Abstract Purpose – The purpose of this paper is to demonstrate why it is essential to understand cultural differences to achieve success in the 21st century. The paper focuses on the adaptations that different industries are incorporating into their business practices to meet the needs of the global consumer. In particular, the paper attempts to address the adaptations that industries are undergoing to cater to ethical and migrationRead MoreWalgreens Analysis2782 Words   |  12 PagesWalgreens Strategy Analysis Retailing: MKTG 3740 B April 7, 2013 I. History and Mission Statement Walgreens has grown from a small, neighborhood-oriented drug store to a trusted, national pharmacy. Founded in 1901 by Charles R. Walgreen, the company bloomed from a commitment made to perseverance. Walgreen came from Dixon, Illinois at the age of sixteen, working an unpleasant job at a drug store after he lost a portion of a finger that left him incapable of continuing a career in athleticsRead MoreThe Atlantic Slave Trade And Analyse What And How Much, African Political And Economic Interests Shaped The Trade Essay2445 Words   |  10 Pagesbegan with the Portuguese on the West African coast in the 15th century, advancing constantly till the 19th century, with a key turning point in the mid 17th century with the booming sugar industry dominating the demand for slave labour. The European demand for slaves was a result of their intentness in profiting from conquests in the New World, and it can be argued that they chose Africans for the trade because of their physical resilience an d resistance towards disease, the comparatively close distance

Unitarism - 1592 Words

Employment Relations Essay Introduction: Unitarism, which also called human resource management, it is an organization is perceived as an integrated and harmonious whole with the ideal of one big happy family, where management and other members of the staff all share a common purpose, emphasizing mutual cooperation. Another opposite approach is pluralism which called industry relationship. There are no common interest in the organization and different loyalty and authority inside. This essay will argue that the unitarism approach is not beneficial for all actors in the employment relationship. And it will do a comparison through different country, China and Australia. Body: Unitarism approach focus on the fixed human resource†¦show more content†¦For example, the Foxconn electronic factory in China, which makes products for major laptop and mobile phone such as Apple, Dell, HP, Sony, Nintendo. At past, it has confirmed that totally 11 employees suicide as the reason with the pressure. Foxconn has the nice work condition and work place. This means that the employees will get more some intangible pressure whether or not the high paid, if they not have a smooth communication with the managers, some people who do not have strong psychology and self release ability, the result will be like Foxconn incident (Tam, 2010). As the two most important roles in the human resource management, if the employers notice the excessive task, the employees will be less pressure felling than non report. Consequently the employees will de stress or dissatisfaction. It also stressful for the employers due to the decision making and manage cost, more flexible emp loyment relationship, it needs more input in order to get a normal organization operating. Exchange the role in original trade union. The employers should be more concerned the relation with employees. The employees will be easily changed or fired within the unitarism approach, without the union and state support, the human resource management will be focus in the individualShow MoreRelatedUnitarism, Pluralism and Radicalism Essay3733 Words   |  15 Pagesshort, this project must conform to normal University standards, including full referencing and a reference list. An executive summary or abstract is not required. Topic: Describe the three main perspectives or approaches to industrial relations (unitarism, pluralism and radicalism) and their more recent adaptations (HRM, neo-institutionalism and labour process theory), and then explain conflict and cooperation at work from these perspectives. Criteria for Assessment: ï‚ · demonstrated understanding ofRead MoreWhat Are Go od Industrial Relations?1934 Words   |  8 Pagestheir unions at the workplace, the actions of the Management, and the behavior of the Government; the researchers have divided the industrial relations into three different categories. These categories of industrial or employment relations include Unitarism, Pluralism, and Radicalism. All these fundamental tenets of industrial relations are based on employee welfare policies, ethical considerations, and resolution of all types of problems related to industrial relations (Cornelius, 2001). This paperRead MoreThe Organization Of Trade Unions1514 Words   |  7 Pages2006) Currently, the unitarism of employment relation and pluralism of employment relation are the major popular theories of employment relation in modern enterprises. The unitarism thinks that all the inner motives of employees will be reflected in the pursuit of reward (Latham and Pinder, 2005). The employment relation is supposed to be a long term partnership between employers and employees who have common interest, the maximized profit (Ulrich and Brockbank, 2005). The unitarism has avoided the conflictRead MoreApproaches and Theories Regarding Industrial Relations1694 Words   |  7 Pagesconsidered in this essay; unitarism, pluralism, and radicalism. They all have different views of workplace relations’ whether it is related to work related conflict, the role of unions or job regulation. The question that we can ask is do any of these theories can be defined as good industrial relations and why. â€Å"Unitarists theory believes that the work organization is held together by common objectives that unite managers and workers† (Barnetson, 2009, Lesson note 6, Unitarism) which means that thereRead MoreEmployment Relationship Is Critical Within The Workplace1056 Words   |  5 Pagesproposed three main frames of reference and their influence on approaches to the employment relationship; Unitarism, Pluralism and Marxism. All these frameworks help to conceptualise the employment relationship and influence the choices that organisations make in relation to managing their human capital. One of the approaches that can be used to conceptualise the employment relationship is unitarism. A unitarist approach views employers and employees as always having common interests whilst attemptingRead MoreEmployee Relations HND 2013 Assignment 1 Essay2437 Words   |  10 Pages(yes) or X (No)) Assessors Name: Ms. Himani Avasthi Date Issued : Contents Question 1: Unitary Perspective; Unitarism is considered to be as a family-type system where the association is alleged to be an incorporated and pleasant atmosphere like a happy family. A principal theory of the unitary approach is all employees and the employers as well in the entire organizationRead MoreA Discussion on Trade Unions and whether Management Should Have the Right to Determine whether They Should Operate within Their Workplace1607 Words   |  7 Pagesmanagement should not have the right to determine whether a union should operate in the workplace. This will be done by looking at the role of the union and by looking from the point of view of each of the three employment relations perspectives: unitarism, pluralism and radicalism. The role of the union The very first unions emerged during the 19th century during the uprising of the industrial capitalist system. These unions were initially small in size and were formed by workers as a platform toRead MoreCollective Bargaining And The Intervention Of Trade Unions1923 Words   |  8 Pagesemployment relations: pluralism, unitarism and Marxism (which will not be discussed in this essay). Pluralism means to consider employees in an enterprise or industry as a group to negotiate with the employers while unitarism tends to look at employees individually and working terms can be negotiated between the employer and individual employee. Pluralism lessens the managerial prerogative but cannot take individual differences into consideration while unitarism is the contrary (Oram, 1984). In accordanceRead MoreConflict in Employment Relationship with Reference to the Unitarist, Pluralist and Marxist Perspective2254 Words   |  10 Pagestrade-off between the firms profit and the income of the em ployee, and the tension between work decisions conditions controlled by the employee and the employer (Boxall John Purcell, 2003). While pluralism is basically the opposite view of unitarism, the Marxist view shares some basic assumptions with pluralism such as Difference of interests and Inevitability of conflict, however, Marxists put power and class at the centre of their analysis, rather than rules regulations (Wergin, 2004). TheRead MoreThe Problem Of Rule By Using A Real Modern Business836 Words   |  4 Pagesimprove their businesses. However, controversy might not be a good thing for manufacturing factories like Foxconn. Because the most important thing for them should be high productivity rather than creative. In other words, comparing to pluralism, unitarism might more match the objective of Foxconn.

Enzyme Inhibition Free Essays

string(68) " can be potent enough to work in vivo at reasonable concentrations\." Enzyme Inhibition Many drugs exert their action by inhibition of an enzyme activity in the body. If the activity of an enzyme is vital to the cell or organism, then inhibition may lead to death of the cell or organism. It is now possible to design new drugs which are enzyme inhibitors once a target enzyme has been identified. We will write a custom essay sample on Enzyme Inhibition or any similar topic only for you Order Now Types of Inhibitors A) Reversible Inhibitors:  The effect of the inhibitor is instantaneous, and it can be removed from the enzyme by dialysis so that the enzyme activity is returned to normal. Such inhibitors interact with the enzyme by weak non-covalent bonds to form an enzyme inhibitor complex. E + I ? EI B) Irreversible Inhibitors:  These inhibitors bind very tightly to the enzyme, sometimes by formation of covalent bonds to form an enzyme inhibitor compound rather than a loose complex. The effect is therefore progressive with time reaching a maximum when all of the enzyme has reacted. This is not easily reversed by simple physical treatments such as dialysis. E + I EI Reversible Inhibition of Enzymes There are three types of reversible enzyme inhibition;  competitive, non-competitive  (also called mixed)  and uncompetitive. Competitive- molecules which closely resemble the substrate in size, shape and charge distribution may also slip into the active site. This may result in reaction i. e. the second molecule is another substrate for the enzyme, or it may result in inhibition because the active site is blocked. The inhibitor has a separate equilibrium with the enzyme. The binding of substrate and inhibitor is mutually exclusive. E + S ? ES E + P, E + I ? EI Each of these equilibria is characterised by a dissociation constant. The first by Km (the Michaelis constant) and the second by Ki which characterises the binding between enzyme and inhibitor. If sufficient [S] is present then eventually the inhibition by I will be overcome. This is the diagnostic test for this type of inhibition. Both I and S compete for the available enzyme. The activity of an enzyme is described by the following equation: (Michaelis- Menton equation) In the presence of a  competitive reversible inhibitor, this equation becomes; So the  Michaelis constant  (which is a reciprocal measure of affinity of E and S) is changed by the factor 1 + [I]/Ki where [I] is the inhibitor concentration and  Ki is the dissociation constant for the equilibrium between E and I. Most importantly,  Vmax is unchanged  Ã¢â‚¬â€œ this is diagnostic for this type of inhibition. Ki is best defined as the concentration of inhibitor required to slow the reaction to half the rate it shows in the absence of inhibitor. It is a reciprocal measure of the affinity of E and I. Lineweaver-Burk Plot for Competitive Reversible Inhibition The  intercept on the y axis represents 1/Vmax. The slope is altered by the factor 1 + [I]/Ki, but the  easiest way to calculate Ki  is from the  ratio of the intercepts on the x axis. Without inhibitor the intercept is -1//Km, with inhibitor it is -1/Km(1+[I]/Ki), so the ratio (bigger over smaller so it is greater than 1) is 1 + [I]/Ki. Easiest way to calculate Ki  is from the  ratio of the intercepts on the x axis. Equation: Other Types of Reversible Inhibition Uncompetitive- This type of reversible inhibition is said to occur when the inhibitor binds with the enzyme-substrate complex rather than the enzyme. Substrate and inhibitor bind dependently. Noncompetitive (Mixed)- This type occurs when the inhibitor binds to both the enzyme and enzyme-substrate complex. Substrate and inhibitor bind independently. Irreversible Inhibition of Enzymes Reversible  means that the timescale of the inhibition is similar to that of the enzyme action, usually measured over a few minutes. Irreversible  means that the enzyme activity is inhibited for times significantly longer than the assay times for the enzyme. It does not necessarily mean that the inhibition will not reverse given sufficient time i. . hours, days or weeks. Some of the most interesting examples of enzyme inhibitors as drugs are those which fall between the two extremes and are sometimes defined as Quasi-Irreversible. These include tight-binding inhibitors, transition state analogues and slowly dissociating intermediates. Tight-Binding inhibitors  and  Transition State Analogues  form high affinity complexes with the enzyme and m ay have Ki values in the order of nanomolar (10-9  mol L-1). The value of Ki will be very important in describing the potency of this type of inhibitor. As a rough guide the inhibitor concentration causing 50% inhibition (I50) is used as a measure of Ki. Slowly Dissociating Intermediates  react with the enzyme to form covalent intermediates which take time to dissociate from the enzyme. A Classification of Enzyme Inhibitors as Drugs For a compound to work as a drug in vivo it will ideally have TWO very important properties. These are; Potency  To work in vivo as an enzyme inhibitor the inhibitor will need to be potent enough so that the dose required is in the order of milligrams to grams. Specificity  If a compound is a nonspecific enzyme inhibitor it is more likely to be toxic and exhibit serious side effects. It may be a poison. Simple Reversible- A simple reversible inhibitor binds to the enzyme and decreases the enzyme activity instantaneously and reverses within the time of the enzyme action. The inhibitor binds non-covalently (ionic interactions, hydrogen bonds, Van Der Waal’s forces) to the enzyme and the strength of binding is of a similar order to the substrate i. e. Ki will be of similar size to Km. For very good reasons, the Km values for enzymes vary between about 10-2  mol L-1  to 10-6mol L-1. Unlikely to be potent enough to work in vivo where competition occurs in a dynamic metabolic situation. For a simple competitive inhibitor the inhibition will be self-limiting. If an enzyme is not rate limiting, it may be necessary to achieve ;90% inhibition before any increase in substrate concentration occurs. To do this the inhibitor concentration needs to be approximately 20 times the Ki value. Conformationally Restricted Competitive Inhibitors- It is possible that a reversible competitive inhibitor which is a conformationally restricted analogue of the substrate will have a much higher affinity for the enzyme han does the substrate and hence can be potent enough to work in vivo at reasonable concentrations. You read "Enzyme Inhibition" in category "Essay examples" Such compounds may have Ki values in the region of 1 x 10-7  mol L-1 Quasi-Irreversible Tight Binding Inhibitors- This is an extension of the previous class i. e. competitive inhibitors which are conformationally res tricted and/or have many non-covalent interactions leading to long lasting complexes. Therefore binding is very tight (Ki in order of 10-9  mol L-1  to 10-10  mol L-1) and these compounds are potent enough to act as drugs in vivo. Transition State Analogues- Theoretically, an analogue of a transition state (or reaction intermediate) for the enzyme catalysed reaction will bind much tighter than an analogue of the substrate. The outcome is a potent and potentially specific inhibitor. Theoretically, Ki values can be very low. In practice if Ki values in the region of Nano molar can be achieved, these are potent enough to work in vivo. As we shall see, there has been much work in this area on proteases including HIV protease and there are now a major class of drugs which has been developed on this principle. Slowly Dissociating Intermediates- Some enzymes form covalent intermediates as part of their mechanism e. g. acetylcholinesterase. It is possible for a compound to act as a pseudo-substrate and be converted into a long lasting intermediate. Such an inhibition is time dependent and in some cases is virtually irreversible. Sometimes the intermediate is hydrolysed in minutes or hours but this is still much longer than the normal enzyme mechanism when the intermediate would last only milliseconds. Examples include the anticholinesterases neostigmine and physostigmine (eserine) and penicillin. Irreversible Nonspecific: a. Heavy metal poisons e. g. cyanide, hydrogen sulphide, carbon monoxide- Some enzymes and other important proteins such as Haemoglobin and Cytochromes, require metals as cofactors. These metals are often transition metals such as Fe, Cu, Mn, Zn and ligands which are electron rich will form co-ordinate covalent bonds with these metals will inactivate these proteins. These bonds are strong and very often these ligands are toxic because of this irreversible inactivation. Cyanide reacts with cytochrome oxidase which is the terminal electron carrier in the electron transport chain by ligand formation with the Cu atom at the centre of its mechanism. Similarly, carbon monoxide complexes with the Fe atom in the haem cofactor of haemoglobin. b. Heavy metal ions e. g. mercury, lead etc. – These are common irreversible inhibitors because of their ability to complex firmly with particular groups in enzymes. These effects can be reversed by treatment with chelating agents such as EDTA (ethylene di-amino tetra acetic acid). c. Thiol poisons e. . alkylating agents, Arsenic (III) Many enzymes contain thiol (-SH) groups in amino acid side chains – cysteine, which are essential for catalytic activity. Any compound which reacts with these functional groups will poison the enzyme. E. g. Iodoacetamide  (alkylating agent) Arsenic- The most toxic form of Arsenic is As (III) as in arsenite AsO2. In this form, Arsenic reacts rapidly with  thiol groups, e specially with dithiols such as lipoic acid which is an essential cofactor for some important enzymes such as pyruvate dehydrogenase and -ketoglutarate dehyrdrogenase. You should remember these enzymes as part of the link reaction and the citric acid cycle. When these enzymes are blocked, respiration stops. Arsenic derivatives have been prepared as very poisonous war gases e. g. Lewisite. antidote called  Dimercaprol (‘British Anti-Lewisite’)  was designed by incorporating two thiols for the poison to react with. The two thiol groups react with the arsenical war gas forming a stable compound and thus stopping it from blocking the thiol groups in lipoic acid. Dimercaprol  is used these days as an antidote to poisoning with heavy metals such as antimony, arsenic, mercury, bismuth, gold, thallium. It is also used in conjunction with pencillamine in the treatment of lead poisoning (see BNF). Specific Irreversible Inhibitors: Affinity Labels (Active site directed irreversible inhibitors)- An analogue of the substrate which binds to the active site of an enzyme, but which contains a chemically reactive group, has the potential to form covalent bonds with side chains at or near the active site. These inhibitors are irreversible and have been very useful in elucidating enzyme mechanisms but their reactive nature makes them likely to be toxic when used in vivo. Mechanism-based Inhibitors (‘suicide reagents’) – The principle of this sort of inhibition is that a pseudo substrate is accepted by the enzyme which then catalyses the production of its own inhibitor which reacts covalently in the active site. Such inhibitors should be specific as well as potent. Certain monoamine oxidase inhibitors have this mechanism, also the -lactamase inhibitors (e. g. clavulanate). The pyridoxal phosphate (vitamin B6) dependent enzymes have been a particular candidate for the development of this kind of inhibitor (e. g. difluoromethyldopa). Enzyme inhibitors: Edrophonium – conformationally restricted competitive reversible, ACE inhibitors – Tight binding, HIV protease inhibitors – Transition state analogues, Neostigmine, Penicillin – Slowly dissociating intermediates DFP – Irreversible group specific reagent, Clavulanate – mechanism-based irreversible inhibitor. Types of Enzyme Inhibitors Simple Reversible| Competitive (also uncompetitive, noncompetitive, mixed)| Simple substrate analogues Michaelis-Menten kinetics Ki in region of Km i. e. 10-2  Ã¢â‚¬â€œ 10-6  M| Restricted Conformation| Rigid shape similar to favoured substrate fit Ki less than Km| e. g. drophonium as inhibitor of acetylcholinesterase| Quasi-Irreversible| Tight Binding Ki can be in region of nanomolar| E. g. ACE inhibitors Captopril, enalapril etc. | | Transition State Analogues. Binding constant theoretically below nanomolar| Inhibitors of proteinases e. g. pepsin, renin, HIV proteinase| | Slowly Dissociating Intermediates à ¢â‚¬â€œ time dependent kinetics| e. g. neostigmine, eserine as anticholinesterases Penicillin| Irreversible| Heavy metal poisons etc| Cyanide, Hydrogen Sulphide, Carbon Monoxide| | Group reagents| e. g. Arsenic (III), Iodoacetamide| | DFP action on esterases| | Affinity labels| TPCK on Chymotrypsin| | Mechanism Based (‘suicide inhibitors’)| e. g. Clavulanate onlactamase| Enzyme Inhibitors as Drugs ENZYME| INHIBITOR(S)| USES| Acetylcholinesterase| Edrophonium Neostigmine Eserine| Myasthenia Gravis Glaucoma Paralytic Ileus| Monoamine Oxidase| Tranylcypramine| Depression| Xanthine Oxidase| Allopurinol| Gout, adjunct to Cancer chemotherapy| Carbonic Anhydrase| Acetazolamide| Diuresis| Dihydrofolate Reductase| Methotrexate| Leukaemia| Transpeptidase| Penicillin| Antibacterial| Cyclo-oxygenase| Aspirin etc. Non-steroidal anti-inflammatory drugs| Analgesia Anti-inflammatory Anti-platelet| Angiotensin Converting Enzyme (ACE)| Captopril, enalapril, lisinopril etc. | Anti-hypertension| Thymidylate Synthetase| Fluorouracil| Cancer chemotherapy| Penicillinase (-lactamase)| Clavulanate etc| Anti-bacterial| HIV proteinase| Saquinovar etc| HIV treatment| Reverse Transcriptase| AZT| HIV treatment| HMG-CoA Reductase| Statins, pravastatin etc. | Coronary Heart Disease| Phospodiesterase V| Viagra| Erectile dysfunction| How to cite Enzyme Inhibition, Essay examples